They get into a wild fight for the garbage, with Chief even biting off another dog's ear. One bag drops, and Chief's pack comes across a rival pack of dogs. The city imports bags of garbage as a means of food for the dogs. On Trash Island, there is a pack of five dogs - Rex (Edward Norton), King (Bob Balaban), Duke (Jeff Goldblum), Boss (Bill Murray), and their leader, Chief (Bryan Cranston). Interpreter Nelson (Frances McDormand)(who translates and commentates on major events in the city) muses 'Whatever happened to man's best friend?'Part One: The Little Pilot The head of the Science Party, Professor Watanabe (Akira Ito), believes the dogs can be cured. The first dog sent there is Spots (Liev Schrieber), the pet/bodyguard of Kobayashi's orphaned nephew Atari (Koyu Rankin). Mayor Kobayashi (Kunichi Nomura) issues a decree that will send all dogs to a quarantined piece of land they call Trash Island. An outbreak of 'snout fever' has been infecting dogs across the country. Centuries later, the Kobayashi family has not forgiven their greatest defeat.We jump ahead to twenty years in the future from now in the Japanese city of Megasaki. The clans fought in battle until a child warrior came forth and decapitated the head of the Kobayashi clan. Two of them worshiped dogs while the Kobayashi clan were cat lovers. The film opens with a legend of a war between three clans. Prologue: The Boy Samurai and The Headless Ancestor